| CONGRESS | SENATOR | TERM BEGAN | TERM ENDED | COMMENTS |
|---|---|---|---|---|
| Class 2 | ||||
| 2nd-8th | John Brown (Anti-Admin, DR) | Jun. 18, 1792 | Mar. 3, 1805 | |
| 9th-11th | Buckner Thurston (DR) | Mar. 4, 1805 | Dec. 18, 1809 | Resigned |
| 11th | Henry Clay (DR, AJ, W) | Jan. 4, 1810 | Mar. 3, 1811 | |
| 12th-13th | George M. Bibb (DR, J, R) | Mar. 4, 1811 | Aug. 23, 1814 | Resigned |
| 13th | George Walker (DR) | Aug. 30, 1814 | Feb. 1, 1815 | Appointed |
| 13th-14th | William T. Barry (DR) | Feb. 2, 1815 | May 1, 1816 | Resigned |
| 14th | Martin D. Hardin (F) | Nov. 13, 1816 | Mar. 3, 1817 | Appointed, then elected |
| 15th-16th | John J. Crittenden (DR, AJ, W, OP, AmKN) | Mar. 4, 1817 | Mar. 3, 1819 | Resigned |
| 16th-20th | Richard M. Johnson (DR, JR, J) | Dec. 10, 1819 | Mar. 3, 1829 | |
| 21st-23rd | George M. Bibb (DR, J, R) | Mar. 4, 1829 | Mar. 3, 1835 | |
| 24th-26th | John J. Crittenden (DR, AJ, W, OP, AmKN) | Mar. 4, 1835 | Mar. 3, 1841 | |
| 27th-29th | James T. Morehead (W) | Mar. 4, 1841 | Mar. 3, 1847 | |
| 30th-32nd | Joseph R. Underwood (W) | Mar. 4, 1847 | Mar. 3, 1853 | |
| 33rd-35th | John B. Thompson (W, OP, AmKN) | Mar. 4, 1853 | Mar. 3, 1859 | |
| 36th-38th | Lazarus W. Powell (D) | Mar. 4, 1859 | Mar. 3, 1865 | |
| 39th-40th | James Guthrie (D) | Mar. 4, 1865 | Feb. 7, 1868 | Resigned |
| 40th-41st | Thomas C. McCreery (D) | Feb. 19, 1868 | Mar. 3, 1871 | |
| 42nd-44th | John W. Stevenson (D) | Mar. 4, 1871 | Mar. 3, 1877 | |
| 45th-51st | James B. Beck (D) | Mar. 4, 1877 | May 3, 1890 | Died |
| 51st-52nd | John G. Carlisle (D) | May 26, 1890 | Feb. 4, 1893 | Resigned |
| 52nd-56th | William Lindsay (D) | Feb. 15, 1893 | Mar. 3, 1901 | |
| 57th-59th | Joseph C. S. Blackburn (D) | Mar. 4, 1901 | Mar. 3, 1907 | |
| 60th-62nd | Thomas H. Paynter (D) | Mar. 4, 1907 | Mar. 3, 1913 | |
| 63rd-65th | Ollie M. James (D) | Mar. 4, 1913 | Aug. 28, 1918 | Died |
| 65th | George B. Martin (D) | Sept. 7, 1918 | Mar. 3, 1919 | Appointed |
| 66th-68th | Augustus O. Stanley (D) | May 19, 19191 | Mar. 3, 1925 | |
| 69th-71st | Frederick M. Sackett (R) | Mar. 4, 1925 | Jan. 9, 1930 | Resigned |
| 71st | John M. Robsion (R) | Jan. 11, 1930 | Nov. 30, 1930 | Appointed |
| 71st | Ben M. Williamson (D) | Dec. 1, 1930 | Mar. 3, 1931 | |
| 72nd-76th | Marvel M. Logan (D) | Mar. 4, 1931 | Oct. 3, 1939 | Died |
| 76th-79th | Happy Chandler (D) | Oct. 10, 1939 | Nov. 1, 1945 | Appointed, then elected; resigned |
| 79th | William A. Stanfill (R) | Nov. 19, 1945 | Nov. 5, 1946 | Appointed |
| 80th | John S. Cooper (R) | Nov. 6, 1946 | Jan. 3, 1949 | |
| 81st-82nd | Virgil M. Chapman (D) | Jan. 3, 1949 | Mar. 8, 1951 | Died |
| 82nd | Thomas R. Underwood (D) | Mar. 19, 1951 | Nov. 4, 1952 | Appointed |
| 82nd-83rd | John S. Cooper (R) | Nov. 5, 1952 | Jan. 3, 1955 | |
| 84th-83rd | Alben W. Barkley (D) | Jan. 3, 1955 | Apr. 30, 1956 | Died |
| 84th | Robert Humphreys (D)2 | Jun. 21, 1956 | Nov. 6, 1956 | Appointed |
| 84th-92nd | John S. Cooper (R) | Nov. 7, 1956 | Jan. 3, 1973 | |
| 93rd-98th | Walter D. Huddleston (D) | Jan. 3, 1973 | Jan. 3, 1985 | |
| 99th- | Mitch McConnell (R) | Jan. 3, 1985 | Present | |
| Class 3 | ||||
| 2nd-3rd | John Edwards (Anti-Admin) | Jun. 18, 1792 | Mar. 3, 1795 | |
| 4th-6th | Humphrey Marshall (F) | Mar. 4, 1795 | Mar. 3, 1801 | |
| 7th-9th | John Breckinridge (DR) | Mar. 4, 1801 | Aug. 7, 1805 | Resigned |
| 9th | John Adair (DR, J) | Nov. 8, 1805 | Nov. 18, 1806 | Resigned |
| 9th | Henry Clay (DR, AJ, W) | Dec. 29, 1806 | Mar. 3, 1807 | |
| 10th-12th | John Pope (DR) | Mar. 4, 1807 | Mar. 3, 1813 | |
| 13th | Jesse Bledsoe (DR)2 | Mar. 4, 1813 | Jan. 14, 1815 | Resigned |
| 13th-15th | Isham Talbot (DR, Adams-Clay R) | Feb. 2, 1815 | Mar. 3, 1819 | |
| 16th | William Logan (DR) | Mar. 4, 1819 | May 28, 1820 | Resigned |
| 16th-18th | Isham Talbot (DR, Adams-Clay R) | Oct. 19, 1820 | Mar. 3, 1825 | |
| 19th-21st | John Rowan (J) | Mar. 4, 1825 | Mar. 3, 1831 | |
| 22nd-27th | Henry Clay (DR, AJ, W) | Nov. 10, 1831 | Mar. 31, 1842 | Resigned |
| 27th-30th | John J. Crittenden (DR, AJ, W, OP, AmKN) | Mar. 31, 1842 | Jun. 12, 1848 | Resigned |
| 30th | Thomas Metcalfe (W) | Jun. 23, 1848 | Mar. 3, 1849 | Appointed, then elected |
| 31st-32nd | Henry Clay (DR, AJ, W) | Mar. 4, 1849 | Jun. 29, 18523 | Resigned |
| 32nd | David Meriwether (D) | Jul. 6, 1852 | Aug. 31, 1852 | Appointed |
| 32nd-33rd | Archibald Dixon (W) | Sept. 1, 1852 | Mar. 3, 1855 | |
| 34th-36th | John J. Crittenden (DR, AJ, W, OP, AmKN) | Mar. 4, 1855 | Mar. 3, 1861 | |
| 37th | John C. Breckinridge (D) | Mar. 4, 1861 | Dec. 4, 1861 | Expelled |
| 37th-42nd | Garrett Davis (U) | Dec. 10, 1861 | Sept. 22, 1872 | Died |
| 42nd | Willis B. Machen (D) | Sept. 27, 1872 | Mar. 3, 1873 | Appointed, then elected |
| 43rd-45th | Thomas C. McCreery (D) | Mar. 4, 1873 | Mar. 3, 1879 | |
| 46th-48th | John S. Williams (D) | Mar. 4, 1879 | Mar. 3, 1885 | |
| 49th-54th | Joseph C. S. Blackburn (D) | Mar. 4, 1885 | Mar. 3, 1897 | |
| 55th-57th | William J. Deboe (R) | Mar. 4, 1897 | Mar. 3, 1903 | |
| 58th-60th | James B. McCreary (D) | Mar. 4, 1903 | Mar. 3, 1909 | |
| 61st-63rd | William O. Bradley (R) | Mar. 4, 1909 | May 23, 1914 | Died |
| 63rd | Johnson N. Camden, Jr. (D) | Jun. 16, 1914 | Mar. 3, 1915 | Appointed, then elected |
| 64th-66th | John C. W. Beckham (D) | Mar. 4, 1915 | Mar. 3, 1921 | |
| 67th-69th | Richard P. Ernst (R) | Mar. 4, 1921 | Mar. 3, 1927 | |
| 70th-81st | Alben W. Barkley (D) | Mar. 4, 1927 | Jan. 19, 19494 | Resigned |
| 81st | Garrett L. Withers (D) | Jan. 20, 1949 | Nov. 26, 1950 | Appointed |
| 81st-84th | Earle C. Clements (D) | Nov. 27, 19505 | Jan. 3, 1957 | |
| 85th-90th | Thruston B. Morton (R) | Jan. 3, 1957 | Dec. 16, 1968 | Resigned |
| 90th-93rd | Marlow W. Cook (R) | Dec. 17, 19686 | Dec. 27, 1974 | Resigned |
| 93rd-105th | Wendell H. Ford (D) | Dec. 28, 19747 | Jan. 3, 1999 | |
| 106th-111th | James P. D. Bunning (R) | Jan. 3, 1999 | Jan. 3, 2011 | |
| 112th- | Rand Paul (R) | Jan. 3, 2011 | Present | |
1. Elected to term commencing March 4, 1919; governor during interim.
2. Joseph J. Leary appointed June 18, 1956, to fill vacancy, but declined to serve.
2. Resignaton offered December 24, 1814, but remained on Senate payroll until January 14, 1815; declared by Senate resolution of Jan. 20, 1815, as having resigned.
3. Resigned Dec. 17, 1851, to take effect first Monday in Sept. 1852. Died June 29, 1852.
4. Resigned Jan. 19, 1949, having been elected vice president of the United States for the 41st term.
5. Elected Nov. 7, 1950, for vacancy in term ending Jan. 3, 1951, and at the same time for full term beginning Jan. 3, 1951. Oath Administered Nov. 27, 1950.
6. Elected to six-year term commencing Jan. 3, 1969, and subsequently appointed by governor to fill vacancy in term ending Jan. 2, 1969.
7. Elected to six-year term commencing Jan. 3, 1975, and subsequently appointed by governor to fill vacancy in term ending Jan. 2, 1975.
