| CONGRESS | SENATOR | TERM BEGAN | TERM ENDED | COMMENTS |
|---|---|---|---|---|
| Class 2 | ||||
| 2nd-8th | John Brown (ANTI-ADMIN, R) | Jun. 18, 1792 | Mar. 3, 1805 | |
| 9th-11th | Buckner Thruston (R) | Mar. 4, 1805 | Dec. 18, 1809 | Resigned |
| 11th | Henry Clay (R) | Jan. 4, 1810 | Mar. 3, 1811 | |
| 12th-13th | George M. Bibb (R) | Mar. 4, 1811 | Aug. 23, 1814 | Resigned |
| 13th | George Walker (R) | Aug. 30, 1814 | Feb. 1, 1815 | Appointed |
| 13th-14th | William T. Barry (R) | Feb. 2, 1815 | May 1, 1816 | Resigned |
| 14th | Martin D. Hardin (F) | Nov. 13, 1816 | Mar. 3, 1817 | Appointed, then elected |
| 15th-16th | John J. Crittenden (R) | Mar. 4, 1817 | Mar. 3, 1819 | Resigned |
| 16th-20th | Richard M. Johnson (R, JR, J) | Dec. 10, 1819 | Mar. 3, 1829 | |
| 21st-23rd | George M. Bibb (J) | Mar. 4, 1829 | Mar. 3, 1835 | |
| 24th-26th | John J. Crittenden (AJ, W) | Mar. 4, 1835 | Mar. 3, 1841 | |
| 27th-29th | James T. Morehead (W) | Mar. 4, 1841 | Mar. 3, 1847 | |
| 30th-32nd | Joseph R. Underwood (W) | Mar. 4, 1847 | Mar. 3, 1853 | |
| 33rd-35th | John B. Thompson (W, OP, AM) | Mar. 4, 1853 | Mar. 3, 1859 | |
| 36th-38th | Lazurus W. Powell (D) | Mar. 4, 1859 | Mar. 3, 1865 | |
| 39th-40th | James Guthrie (D) | Mar. 4, 1865 | Feb. 7, 1868 | Resigned |
| 40th-41st | Thomas C. McCreery (D) | Feb. 19, 1868 | Mar. 3, 1871 | |
| 42nd-44th | John W. Stevenson (D) | Mar. 4, 1871 | Mar. 3, 1877 | |
| 45th-51st | James B. Beck (D) | Mar. 4, 1877 | May 3, 1890 | Died |
| 51st-52nd | John G. Carlisle (D) | May 17, 1890 | Feb. 4, 1893 | Resigned |
| 52nd-56th | William Lindsay (D) | Feb. 15, 1893 | Mar. 3, 1901 | |
| 57th-59th | Joseph C.S. Blackburn (D) | Mar. 4, 1901 | Mar. 3, 1907 | |
| 60th-62nd | Thomas H. Paynter (D) | Mar. 4, 1907 | Mar. 3, 1913 | |
| 63rd-65th | Ollie M. James (D) | Mar. 4, 1913 | Aug. 28, 1918 | Died |
| 65th | George B. Martin (D) | Sept. 7, 1918 | Mar. 3, 1919 | Appointed |
| 66th-68th | A. Owsley Stanley (D) | Mar. 4, 1919 | Mar. 3, 1925 | |
| 69th-71st | Frederic M. Sackett (R) | Mar. 4, 1925 | Jan. 9, 1930 | Resigned |
| 71st | John M. Robsion (R) | Jan. 11, 1930 | Nov. 30, 1930 | Appointed |
| 71st | Ben M. Williamson (D) | Dec. 1, 1930 | Mar. 3, 1931 | |
| 72nd-76th | Marvel M. Logan (D) | Mar. 4, 1931 | Oct. 3, 1939 | Died |
| 76th-79th | Albert B. Chandler (D) | Oct. 10, 1939 | Nov. 1, 1945 | Appointed, then elected; resigned |
| 79th | William A. Stanfill (R) | Nov. 19, 1945 | Nov. 5, 1946 | Appointed |
| 80th | John Sherman Cooper (R) | Nov. 6, 1946 | Jan. 3, 1949 | |
| 81st-82nd | Virgil M. Chapman (D) | Jan. 3, 1949 | Mar. 8, 1951 | Died |
| 82nd | Thomas R. Underwood (D) | Mar. 19, 1951 | Nov. 4, 1952 | Appointed |
| 82nd-83rd | John Sherman Cooper (R) | Nov. 5, 1952 | Jan. 3, 1955 | |
| 84th-83rd | Alben W. Barkley (D) | Jan. 3, 1955 | Apr. 30, 1956 | Died |
| 84th | Robert Humphreys1 (D) | Jun. 21, 1956 | Nov. 6, 1956 | Appointed |
| 84th-92nd | John Sherman Cooper (R) | Nov. 7, 1956 | Jan. 3, 1973 | |
| 93rd-98th | Walter D. Huddleston (D) | Jan. 3, 1973 | Jan. 3, 1985 | |
| 99th- | Mitch McConnell (R) | Jan. 3, 1985 | Present | |
| Class 3 | ||||
| 2nd-3rd | John Edwards (ANTI-ADMIN) | Jun. 18, 1792 | Mar. 3, 1795 | |
| 4th-6th | Humphrey Marshall (F) | Mar. 4, 1795 | Mar. 3, 1801 | |
| 7th-9th | John Breckinridge (R) | Mar. 4, 1801 | Aug. 7, 1805 | Resigned |
| 9th | John Adair (R) | Nov. 8, 1805 | Nov. 18, 1806 | Resigned |
| 9th | Henry Clay (R) | Dec. 29, 1806 | Mar. 3, 1807 | |
| 10th-12th | John Pope (R) | Mar. 4, 1807 | Mar. 3, 1813 | |
| 13th | Jesse Bledsoe2 (R) | Mar. 4, 1813 | Jan. 14, 1815 | Resigned |
| 13th-15th | Isham Talbot (R) | Feb. 2, 1815 | Mar. 3, 1819 | |
| 16th | William Logan (R) | Mar. 4, 1819 | May 28, 1820 | Resigned |
| 16th-18th | Isham Talbot (R, ADAMS-CLAY R) | Oct. 19, 1820 | Mar. 3, 1825 | |
| 19th-21st | John Rowan (J) | Mar. 4, 1825 | Mar. 3, 1831 | |
| 22nd-27th | Henry Clay (AJ, W) | Nov. 10, 1831 | Mar. 31, 1842 | Resigned |
| 27th-30th | John J. Crittenden (W) | Mar. 31, 1842 | Jun. 12, 1848 | Resigned |
| 30th | Thomas Metcalfe (W) | Jun. 23, 1848 | Mar. 3, 1849 | Appointed, then elected |
| 31st-32nd | Henry Clay (W) | Mar. 4, 1849 | Jun. 29, 18523 | Resigned |
| 32nd | David Meriwether (D) | Jul. 6, 1852 | Sept. 1, 1852 | Appointed |
| 32nd-33rd | Archibald Dixon (W) | Sept. 1, 1852 | Mar. 3, 1855 | |
| 34th-36th | John J. Crittenden (OP, AM) | Mar. 4, 1855 | Mar. 3, 1861 | |
| 37th | John C. Breckinridge (D) | Mar. 4, 1861 | Dec. 4, 1861 | Expelled |
| 37th-42nd | Garrett Davis (U, D) | Dec. 10, 1861 | Sept. 22, 1872 | Died |
| 42nd | Willis B. Machen (D) | Sept. 27, 1872 | Mar. 3, 1873 | Appointed, then elected |
| 43rd-45th | Thomas C. McCreery (D) | Mar. 4, 1873 | Mar. 3, 1879 | |
| 46th-48th | John Stuart Williams (D) | Mar. 4, 1879 | Mar. 3, 1885 | |
| 49th-54th | Joseph C.S. Blackburn (D) | Mar. 4, 1885 | Mar. 3, 1897 | |
| 55th-57th | William J. Deboe (R) | Mar. 4, 1897 | Mar. 3, 1903 | |
| 58th-60th | James B. McCreary (D) | Mar. 4, 1903 | Mar. 3, 1909 | |
| 61st-63rd | William O. Bradley (R) | Mar. 4, 1909 | May 23, 1914 | Died |
| 63rd | Johnson N. Camden Jr. (D) | Jun. 16, 1914 | Mar. 3, 1915 | Appointed, then elected |
| 64th-66th | John C.W. Beckham (D) | Mar. 4, 1915 | Mar. 3, 1921 | |
| 67th-69th | Richard P. Ernst (R) | Mar. 4, 1921 | Mar. 3, 1927 | |
| 70th-81st | Alben W. Barkley (D) | Mar. 4, 1927 | Jan. 19, 19494 | Resigned |
| 81st | Garrett L. Withers (D) | Jan. 20, 1949 | Nov. 26, 1950 | Appointed |
| 81st-84th | Earle C. Clements (D) | Nov. 27, 19505 | Jan. 3, 1957 | |
| 85th-90th | Thruston B. Morton (R) | Jan. 3, 1957 | Dec. 16, 1968 | Resigned |
| 90th-93rd | Marlow W. Cook (R) | Dec. 17, 19686 | Dec. 27, 1974 | Resigned |
| 93rd-105th | Wendell H. Ford (D) | Dec. 28, 19747 | Jan. 3, 1999 | |
| 106th-111th | Jim Bunning (R) | Jan. 3, 1999 | Jan. 3, 2011 | |
| 112th- | Rand Paul (R) | Jan. 3, 2011 | Present | |
1. Joseph J. Leary appointed June 18, 1956, to fill vacancy, but declined to serve.
2. Resignaton offered December 24, 1814, but remained on Senate payroll until January 14, 1815; declared by Senate resolution of Jan. 20, 1815, as having resigned.
3. Resigned Dec. 17, 1851, to take effect first Monday in Sept. 1852. Died June 29, 1852.
4. Resigned Jan. 19, 1949, having been elected vice president of the United States for the 41st term.
5. Elected Nov. 7, 1950, for vacancy in term ending Jan. 3, 1951, and at the same time for full term beginning Jan. 3, 1951. Oath Administered Nov. 27, 1950.
6. Elected to six-year term commencing Jan. 3, 1969, and subsequently appointed by governor to fill vacancy in term ending Jan. 2, 1969.
7. Elected to six-year term commencing Jan. 3, 1975, and subsequently appointed by governor to fill vacancy in term ending Jan. 2, 1975.
