| CONGRESS | SENATOR | TERM BEGAN | TERM ENDED | COMMENTS |
|---|---|---|---|---|
| Class 1 | ||||
| 4th | William Cocke (DR) | Aug. 2, 1796 | Mar. 3, 1797 | |
| 5th | William Cocke (DR) | Apr. 22, 17971 | Sept. 26, 1797 | Appointed |
| 5th | Andrew Jackson (DR) | Sept. 26, 1797 | Apr. 1798 | Resigned |
| 5th | Daniel Smith (DR) | Oct. 6, 1798 | Mar. 3, 1799 | Appointed |
| 5th-13th | Joseph I. Anderson (DR) | Mar. 4, 17992 | Mar. 3, 1815 | |
| 14th-16th | George W. Campbell (DR) | Oct. 10, 18153 | Apr. 20, 1818 | Resigned |
| 15th-21st | John H. Eaton (DR, JR, J) | Sept. 5, 1818 | Mar. 9, 1829 | Appointed, then elected; resigned |
| 21st-25th | Felix Grundy (J, D) | Oct. 19, 1829 | Jul. 4, 1838 | Resigned |
| 25th | Ephraim H. Foster (W)4 | Sept. 17, 1838 | Mar. 3, 1839 | Resigned |
| 26th | Felix Grundy (J, D) | Dec. 14, 1839 | Dec. 19, 1840 | Died |
| 26th-27th | Alfred O. P. Nicholson (D) | Dec. 25, 1840 | Feb. 7, 1842 | Appointed |
| 28th | Ephraim H. Foster (W) | Oct. 17, 18435 | Mar. 3, 1845 | |
| 29th-31st | Hopkins L. Turney (D) | Mar. 4, 1845 | Mar. 3, 1851 | |
| 32nd-34th | James C. Jones (W) | Mar. 4, 1851 | Mar. 3, 1857 | |
| 35th-37th | Andrew Johnson (D) | Oct. 8, 18576 | Mar. 3, 18637 | |
| 39th-40th | David T. Patterson (U) | Jul. 24, 18668 | Mar. 3, 1869 | |
| 41st-43rd | William Gannaway Brownlow (R) | Mar. 4, 1869 | Mar. 3, 1875 | |
| 44th | Andrew Johnson (D) | Mar. 4, 1875 | Jul. 31, 1875 | |
| 44th | David M. Key (D) | Aug. 18, 1875 | Jan. 19, 1877 | Appointed |
| 44th-46th | James E. Bailey (D) | Jan. 19, 1877 | Mar. 3, 1881 | |
| 47th-49th | Howell E. Jackson (D) | Mar. 4, 1881 | Apr. 14, 1886 | Resigned |
| 49th | Washington C. Whitthorne (D) | Apr. 16, 1886 | Mar. 3, 1887 | Appointed |
| 50th-59th | William B. Bate (D) | Mar. 4, 1887 | Mar. 9, 1905 | Died |
| 59th-61st | James B. Frazier (D) | Mar. 21, 1905 | Mar. 3, 1911 | |
| 62nd | Luke Lea (D) | Mar. 4, 1911 | Mar. 3, 1917 | |
| 65th-82nd | Kenneth D. McKellar (D) | Mar. 4, 1917 | Jan. 3, 1953 | |
| 83rd-91st | Albert A. Gore (D) | Jan. 3, 1953 | Jan. 3, 1971 | |
| 92nd-94th | William E. Brock III (R) | Jan. 3, 1971 | Jan. 3, 1977 | |
| 95th-103rd | James R. Sasser (D) | Jan. 3, 1977 | Jan. 3, 1995 | |
| 104th-109th | William H. Frist (R) | Jan. 3, 1995 | Jan. 3, 2007 | |
| 110th-115th | Bob Corker (R) | Jan. 3, 2007 | Jan. 3, 2019 | |
| 116th- | Marsha Blackburn (R) | Jan. 3, 2019 | Present | |
| Class 2 | ||||
| 4th-5th | William Blount (DR) | Aug. 2, 1796 | Jul. 8, 1797 | Expelled |
| 5th | Joseph I. Anderson (DR) | Sept. 26, 1797 | Mar. 3, 1799 | |
| 6th-8th | William Cocke (DR) | Mar. 4, 1799 | Mar. 3, 1805 | |
| 9th-11th | Daniel Smith (DR) | Mar. 4, 1805 | Mar. 31, 1809 | Resigned |
| 11th-12th | Jenkin Whiteside (DR) | Apr. 11, 1809 | Oct. 8, 1811 | Resigned |
| 12th-13th | George W. Campbell (DR) | Oct. 8, 1811 | Feb. 11, 1814 | Resigned |
| 13th-14th | Jesse Wharton (DR) | Mar. 17, 1814 | Oct. 10, 1815 | Appointed |
| 14th-17th | John Williams (DR)9 | Oct. 10, 1815 | Mar. 3, 1823 | |
| 18th-19th | Andrew Jackson (DR) | Mar. 4, 1823 | Oct. 14, 1825 | Resigned |
| 19th-26th | Hugh L. White (J, AJ, W) | Oct. 28, 1825 | Jan. 13, 1840 | Resigned |
| 26th | Alexander Outlaw Anderson (D) | Jan. 27, 1840 | Mar. 3, 1841 | |
| 28th-29th | Spencer Jarnagin (W) | Oct. 17, 184310 | Mar. 3, 1847 | |
| 30th-35th | John Bell (W, OP, AmKN)12 | Nov. 22, 184711 | Mar. 3, 1859 | |
| 36th-38th | Alfred O. P. Nicholson (D) | Mar. 4, 1859 | Mar. 3, 186113 | |
| 39th-41st | Joseph S. Fowler (UU, R) | Jul. 24, 186614 | Mar. 3, 1871 | |
| 42nd-44th | Henry Cooper (D) | Mar. 4, 1871 | Mar. 3, 1877 | |
| 45th-55th | Isham G. Harris (D) | Mar. 4, 1877 | Jul. 8, 1897 | Died |
| 55th-56th | Thomas B. Turley (D) | Jul. 20, 1897 | Mar. 3, 1901 | Appointed, then elected |
| 57th-59th | Edward W. Carmack (D) | Mar. 4, 1901 | Mar. 3, 1907 | |
| 60th-62nd | Robert L. Taylor (D) | Mar. 4, 1907 | Mar. 31, 1912 | Died |
| 62nd | Newell Sanders (R) | Apr. 8, 1912 | Jan. 24, 1913 | Appointed |
| 62nd | William Robert Webb (D) | Jan. 24, 1913 | Mar. 3, 1913 | |
| 63rd-68th | John K. Shields (D) | Mar. 4, 1913 | Mar. 3, 1925 | |
| 69th-71st | Lawrence D. Tyson (D) | Mar. 4, 1925 | Aug. 24, 1929 | Died |
| 71st | William E. Brock (D) | Sept. 2, 1929 | Mar. 3, 1931 | Appointed, then elected |
| 72nd-73rd | Cordell Hull (D) | Mar. 4, 1931 | Mar. 3, 1933 | Resigned |
| 73rd-75th | Nathan L. Bachman (D) | Mar. 4, 1933 | Apr. 23, 1937 | Appointed, then elected; died |
| 75th | George L. Berry (D) | May 6, 1937 | Nov. 8, 1938 | Appointed |
| 75th-80th | A. Thomas Stewart (D) | Jan. 16, 193915 | Jan. 3, 1949 | |
| 81st-88th | Carey Estes Kefauver (D) | Jan. 3, 1949 | Aug. 10, 1963 | Died |
| 88th | Herbert S. Walters (D) | Aug. 20, 1963 | Nov. 3, 1964 | Appointed |
| 88th-89th | Ross Bass (D) | Nov. 4, 1964 | Jan. 3, 1967 | |
| 90th-98th | Howard H. Baker, Jr. (R) | Jan. 3, 1967 | Jan. 3, 1985 | |
| 99th-103rd | Albert A. Gore, Jr. (D) | Jan. 3, 1985 | Jan. 2, 199316 | Resigned |
| 103rd | Harlan Mathews (D) | Jan. 2, 1993 | Dec. 1, 1994 | Appointed |
| 103rd-107th | Fred D. Thompson (R) | Dec. 2, 1994 | Jan. 3, 2003 | |
| 108th-116th | Lamar Alexander (R) | Jan. 3, 2003 | Jan. 3, 2021 | |
| 117th- | Bill Hagerty (R) | Jan. 3, 2021 | Present | |
1. By governor, to fill vacancy because of legislature's failure to elect.
2. Elected on Dec. 12, 1798, but still served in the other Tennessee seat until Mar. 3, 1799.
3. Vacancy from Mar. 1 to Oct. 10, 1815, because of failure of legislature to elect.
4. By governor, to fill vacancy; subsequently elected for term beginning Mar. 4, 1839; resigned Mar. 3, 1839. Vacancy from Mar. 4, to Dec. 14, 1839.
5. Vacancy from Feb. 8, 1842 to Oct 16, 1843.
6. Vacancy from Mar. 4, to Oct. 7, 1857.
7. Resigned Mar. 4, 1862, to become military governor of Tennessee. Because of Civil War, vacancy from Mar. 4, 1862, to July 24, 1866, when Tennessee was readmitted to representation.
8. Elected by legislature, to fill vacancy in term beginning Mar. 4, 1863. Seated July 28, 1866, after the Senate resolved a challenge to his seating.
9. Between Mar. 14 and Oct 1, 1817, Williams was appointed by the governor, during recess of legislature. Subsequently reelected.
10. Vacancy from Mar. 4, 1841 to Oct. 16, 1843.
11. Vacancy from Mar. 4, 1847 to Nov. 21, 1847.
12. The seat Bell occupied was actually vacancy from Mar. 4 to Oct. 28, 1853.
13. Withdrew Mar. 3, 1861. Expelled July 11, 1861. Because of Civil War, vacancy from Mar. 3, 1861, to July 24, 1866, when Tennessee was readmitted to representation.
14. By legislature to fill vacancy in term beginning Mar. 4, 1865. Seated July 25, 1866.
15. Elected Nov. 8, 1938, but did not assume duties until Jan. 16, 1939. Vacancy from Nov. 9, 1938 to Jan. 15, 1939.
16. Resigned Jan. 2, 1993, having been elected vice president of the United States for the 52nd term on Nov. 3, 1992.
